STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICE1Interactor of little elongation complex ELL subunit 1. (2267 aa)    
Predicted Functional Partners:
ICE2
Interactor of little elongation complex ELL subunit 2.
    
 0.954
ZC3H8
Zinc finger CCCH-type containing 8.
   
 
 0.876
ELL3
Elongation factor for RNA polymerase II 3.
    
 0.799
RPAP2
RTR1-type domain-containing protein.
     
 0.742
ELL
Elongation factor for RNA polymerase II.
   
 0.727
ELL2
Elongation factor for RNA polymerase II 2.
   
 0.676
RPRD2
Regulation of nuclear pre-mRNA domain containing 2.
   
 
 0.586
YJU2
YJU2 splicing factor homolog.
   
  
 0.561
INTS12
Integrator complex subunit 12.
   
 0.556
EAF1
ELL associated factor 1.
   
 
 0.546
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.