STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INAInternexin neuronal intermediate filament protein alpha; Belongs to the intermediate filament family. (500 aa)    
Predicted Functional Partners:
NEFL
Neurofilament light; Belongs to the intermediate filament family.
   
 
0.918
NEFH
Neurofilament heavy; Belongs to the intermediate filament family.
   
 
0.793
NEFM
Neurofilament medium; Belongs to the intermediate filament family.
   
 
0.690
SH2D2A
SH2 domain containing 2A.
      
 0.641
GAN
Gigaxonin.
   
 
 0.599
RSAD1
Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 
 0.567
CDK5RAP3
CDK5 regulatory subunit associated protein 3.
   
 
 0.517
WDR27
WD repeat domain 27.
   
 
 0.499
FAM187A
Family with sequence similarity 187 member A.
   
 
 0.492
UBQLN4
Ubiquilin 4.
   
 
 0.474
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.