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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL12Adiponectin receptor 1. (914 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 
 0.917
DVL1
Dishevelled segment polarity protein 1.
   
 
 0.872
PEF1
Penta-EF-hand domain containing 1.
   
 
 0.765
SEC31A
SEC31 homolog A, COPII coat complex component.
   
 
 0.718
DVL3
Dishevelled segment polarity protein 3.
   
 
 0.695
SEC22B
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
   
  
 0.675
FBXL17
F-box and leucine rich repeat protein 17.
   
 
 0.612
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
   
 
 0.608
DVL2
Dishevelled segment polarity protein 2.
    
 
 0.601
SEC16A
Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
   
 
 0.597
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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