STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC119BUnc-119 lipid binding chaperone B. (250 aa)    
Predicted Functional Partners:
ARL3
ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.
   
 0.986
NPHP3
Nephrocystin 3.
    
 0.943
RP2
RP2 activator of ARL3 GTPase.
   
 
 0.904
CCDC71
Coiled-coil domain containing 71.
   
  
 0.876
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...]
  
  
 0.751
EXOSC4
Exosome component 4.
      
 0.671
DNAJC11
DnaJ heat shock protein family (Hsp40) member C11.
   
 
 0.626
TOB2
Transducer of ERBB2, 2.
    
 
 0.622
URB2
URB2 ribosome biogenesis homolog.
   
 
 0.592
GLIS2
GLIS family zinc finger 2.
   
 
 0.590
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.