STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UNC119BUnc-119 lipid binding chaperone B. (250 aa)    
Predicted Functional Partners:
NPHP3
Nephrocystin 3.
    
 0.983
ARL3
ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.
    
 0.942
UNC119
Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Proba [...]
   
 
 0.933
RP2
RP2 activator of ARL3 GTPase.
     
 0.905
CCDC71
Coiled-coil domain containing 71.
   
  
 0.890
PSKH2
Protein serine kinase H2; Belongs to the protein kinase superfamily.
    
 0.872
AVPI1
Arginine vasopressin induced 1.
    
   0.788
RNF34
Ring finger protein 34.
   
   0.784
CHTOP
Chromatin target of PRMT1.
      
 0.776
PALD1
Phosphatase domain containing paladin 1.
    
   0.749
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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