STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRX1Iroquois homeobox 1. (511 aa)    
Predicted Functional Partners:
IRX4
Iroquois homeobox 4.
 
 
 
 0.841
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif 16.
   
  
 0.804
DLX1
Distal-less homeobox 1.
   
 
 0.723
DLX2
Distal-less homeobox 2.
   
 
 0.721
FOXP1
Forkhead box P1.
      
 0.692
GALNT13
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.672
CSRP1
Cysteine and glycine rich protein 1.
   
  
 0.666
CLK4
CDC like kinase 4; Belongs to the protein kinase superfamily.
   
  
 0.655
HHEX
Hematopoietically expressed homeobox.
   
 
 0.637
ANHX
Anomalous homeobox.
   
  
 0.598
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.