STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCPSDecapping enzyme, scavenger. (443 aa)    
Predicted Functional Partners:
MRPL3
Mitochondrial ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
   
  
 0.808
ENSCAFP00000066593
C2H2-type domain-containing protein.
   
  
 0.768
NCKAP1
NCK associated protein 1.
      
 0.673
RPL14
Uncharacterized protein.
      
 0.670
KANK2
KN motif and ankyrin repeat domains 2.
      
 0.646
LSM12
LSM12 homolog.
   
  
 0.640
GALE
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
   
  
 0.639
SSR1
Translocon-associated protein subunit alpha; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins; Belongs to the TRAP-alpha family.
   
  
 0.636
IST1
IST1 factor associated with ESCRT-III.
   
  
 0.618
SH3KBP1
SH3 domain containing kinase binding protein 1.
      
 0.617
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.