DHCR7 protein (Canis lupus familiaris) - STRING interaction network

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Score

DHCR7

7-dehydrocholesterol reductase. (475 aa)

Predicted Functional Partners:

DHCR24

0.994

SC5D

0.992

NSDHL

0.950

SQLE

0.946

CYP7A1

0.942

CYP51A1

0.935

CYP27A1

0.926

CYP46A1

0.921

SOAT1

0.917

CYP11A1

0.914

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP11A1	CYP27A1	ENSCAFP00000026404	ENSCAFP00000022013	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.621
CYP11A1	CYP46A1	ENSCAFP00000026404	ENSCAFP00000026316	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 46 subfamily A member 1.	0.608
CYP11A1	CYP51A1	ENSCAFP00000026404	ENSCAFP00000002855	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.	0.408
CYP11A1	CYP7A1	ENSCAFP00000026404	ENSCAFP00000045160	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family.	0.452
CYP11A1	DHCR24	ENSCAFP00000026404	ENSCAFP00000028027	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	24-dehydrocholesterol reductase.	0.896
CYP11A1	DHCR7	ENSCAFP00000026404	ENSCAFP00000015326	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	7-dehydrocholesterol reductase.	0.914
CYP11A1	SOAT1	ENSCAFP00000026404	ENSCAFP00000043869	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	O-acyltransferase.	0.897
CYP27A1	CYP11A1	ENSCAFP00000022013	ENSCAFP00000026404	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.621
CYP27A1	CYP46A1	ENSCAFP00000022013	ENSCAFP00000026316	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 46 subfamily A member 1.	0.937
CYP27A1	CYP51A1	ENSCAFP00000022013	ENSCAFP00000002855	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.	0.410
CYP27A1	CYP7A1	ENSCAFP00000022013	ENSCAFP00000045160	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family.	0.980
CYP27A1	DHCR24	ENSCAFP00000022013	ENSCAFP00000028027	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	24-dehydrocholesterol reductase.	0.896
CYP27A1	DHCR7	ENSCAFP00000022013	ENSCAFP00000015326	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	7-dehydrocholesterol reductase.	0.926
CYP27A1	NSDHL	ENSCAFP00000022013	ENSCAFP00000028277	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.	0.659
CYP27A1	SOAT1	ENSCAFP00000022013	ENSCAFP00000043869	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	O-acyltransferase.	0.903
CYP27A1	SQLE	ENSCAFP00000022013	ENSCAFP00000034027	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Squalene epoxidase.	0.412
CYP46A1	CYP11A1	ENSCAFP00000026316	ENSCAFP00000026404	Cytochrome P450 family 46 subfamily A member 1.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.608
CYP46A1	CYP27A1	ENSCAFP00000026316	ENSCAFP00000022013	Cytochrome P450 family 46 subfamily A member 1.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.937
CYP46A1	CYP51A1	ENSCAFP00000026316	ENSCAFP00000002855	Cytochrome P450 family 46 subfamily A member 1.	Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.	0.470
CYP46A1	CYP7A1	ENSCAFP00000026316	ENSCAFP00000045160	Cytochrome P450 family 46 subfamily A member 1.	Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family.	0.940