STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRX2Iroquois homeobox 2. (472 aa)    
Predicted Functional Partners:
IRX1
Iroquois homeobox 1.
   
  
0.746
IRX3
Iroquois homeobox 3.
   
  
0.675
LRRIQ1
Leucine rich repeats and IQ motif containing 1.
      
 0.592
HOXD12
Homeobox D12.
    
 
 0.577
DACH1
Dachshund family transcription factor 1.
      
 0.545
TSHZ3
Teashirt zinc finger homeobox 3.
   
 0.523
DLX2
Distal-less homeobox 2.
   
 
 0.497
DLX1
Distal-less homeobox 1.
   
 
 0.486
IRX4
Iroquois homeobox 4.
   
  
 0.466
SRF
Serum response factor.
   
 
 0.440
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.