STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHANK2SH3 and multiple ankyrin repeat domains 2. (1476 aa)    
Predicted Functional Partners:
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.902
DLGAP1
DLG associated protein 1.
   
 
 0.881
DLGAP2
DLG associated protein 2.
   
 
 0.872
DHRS7B
Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
   0.859
SYNGAP1
Synaptic Ras GTPase activating protein 1.
   
 
 0.856
DLGAP3
DLG associated protein 3.
   
 0.855
DLGAP4
DLG associated protein 4.
   
 0.822
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
   
 0.816
LZTS3
Leucine zipper tumor suppressor family member 3.
     
 0.815
DLG2
Discs large MAGUK scaffold protein 2.
    
 0.787
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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