STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHANK2SH3 and multiple ankyrin repeat domains 2. (1476 aa)    
Predicted Functional Partners:
DLGAP1
DLG associated protein 1.
    
 0.800
DLGAP4
DLG associated protein 4.
    
 0.793
DLGAP3
DLG associated protein 3.
    
 0.793
DLGAP2
DLG associated protein 2.
   
 0.784
NLGN3
Neuroligin 3.
   
 0.771
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.766
CTTN
Cortactin.
    
 
 0.756
NLGN2
Neuroligin 2.
   
 0.741
NLGN1
Neuroligin 1.
    
 0.736
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
    
 
 0.723
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.