STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (633 aa)    
Predicted Functional Partners:
ACE2
Angiotensin-converting enzyme.
   
 
 0.843
NF1
Neurofibromin 1.
   
 
 0.739
SLC36A2
Solute carrier family 36 member 2.
   
  
 0.717
SLC1A1
Amino acid transporter.
  
 
 0.601
SLC1A6
Excitatory amino acid transporter 4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which [...]
  
 
 0.591
SLC12A3
Solute carrier family 12 member 3.
   
  
 0.560
SLC43A2
Solute carrier family 43 member 2.
      
 0.559
ACE
Angiotensin-converting enzyme.
   
 
 0.554
LOC100856208
Angiotensin-converting enzyme.
   
 
 0.554
SLC43A1
Large neutral amino acids transporter small subunit 3.
   
  
 0.539
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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