STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HNF1AHNF1 homeobox A. (638 aa)    
Predicted Functional Partners:
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
    
 
 0.905
PCBD1
Pterin-4 alpha-carbinolamine dehydratase 1.
    
 
 0.902
RPS16
Dual specificity tyrosine phosphorylation regulated kinase 1B.
   
 
 0.731
GCK
Phosphotransferase.
      
 0.610
EP300
E1A binding protein p300.
    
 
 0.606
CREBBP
CREB binding protein.
    
 
 0.602
FOXA2
Forkhead box A2.
      
 0.597
KANK2
KN motif and ankyrin repeat domains 2.
      
 0.578
ABCC8
ATP binding cassette subfamily C member 8.
   
  
 0.567
SREBF2
Sterol regulatory element binding transcription factor 2.
      
 0.551
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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