FIGN protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

FIGN

Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (693 aa)

Predicted Functional Partners:

ZNF703

0.830

PRPF40B

0.786

ZNF503

0.741

IST1

0.737

DYNLRB2

0.735

CHMP1A

0.721

PHTF2

0.715

YOD1

0.711

SHPRH

0.646

ARID3B

0.635

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID3B	FIGN	ENSCAFP00000054764	ENSCAFP00000015470	AT-rich interaction domain 3B.	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	0.635
ARID3B	PHTF2	ENSCAFP00000054764	ENSCAFP00000006473	AT-rich interaction domain 3B.	Putative homeodomain transcription factor 2.	0.824
ARID3B	SHPRH	ENSCAFP00000054764	ENSCAFP00000051164	AT-rich interaction domain 3B.	SNF2 histone linker PHD RING helicase.	0.806
ARID3B	YOD1	ENSCAFP00000054764	ENSCAFP00000016941	AT-rich interaction domain 3B.	YOD1 deubiquitinase.	0.699
CHMP1A	FIGN	ENSCAFP00000032438	ENSCAFP00000015470	Charged multivesicular body protein 1A.	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	0.721
CHMP1A	IST1	ENSCAFP00000032438	ENSCAFP00000029984	Charged multivesicular body protein 1A.	IST1 factor associated with ESCRT-III.	0.917
DYNLRB2	FIGN	ENSCAFP00000029670	ENSCAFP00000015470	Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	0.735
DYNLRB2	PRPF40B	ENSCAFP00000029670	ENSCAFP00000012513	Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.	Pre-mRNA processing factor 40 homolog B.	0.775
FIGN	ARID3B	ENSCAFP00000015470	ENSCAFP00000054764	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	AT-rich interaction domain 3B.	0.635
FIGN	CHMP1A	ENSCAFP00000015470	ENSCAFP00000032438	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Charged multivesicular body protein 1A.	0.721
FIGN	DYNLRB2	ENSCAFP00000015470	ENSCAFP00000029670	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.	0.735
FIGN	IST1	ENSCAFP00000015470	ENSCAFP00000029984	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	IST1 factor associated with ESCRT-III.	0.737
FIGN	PHTF2	ENSCAFP00000015470	ENSCAFP00000006473	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Putative homeodomain transcription factor 2.	0.715
FIGN	PRPF40B	ENSCAFP00000015470	ENSCAFP00000012513	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Pre-mRNA processing factor 40 homolog B.	0.786
FIGN	SHPRH	ENSCAFP00000015470	ENSCAFP00000051164	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	SNF2 histone linker PHD RING helicase.	0.646
FIGN	YOD1	ENSCAFP00000015470	ENSCAFP00000016941	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	YOD1 deubiquitinase.	0.711
FIGN	ZNF503	ENSCAFP00000015470	ENSCAFP00000022724	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Zinc finger protein 503.	0.741
FIGN	ZNF703	ENSCAFP00000015470	ENSCAFP00000009330	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	Zinc finger protein 703.	0.830
IST1	CHMP1A	ENSCAFP00000029984	ENSCAFP00000032438	IST1 factor associated with ESCRT-III.	Charged multivesicular body protein 1A.	0.917
IST1	FIGN	ENSCAFP00000029984	ENSCAFP00000015470	IST1 factor associated with ESCRT-III.	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.	0.737