PKNOX1 protein (Canis lupus familiaris) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

PKNOX1

PBX/knotted 1 homeobox 1. (436 aa)

Predicted Functional Partners:

MYBBP1A

0.725

MED30

0.657

PBX4

0.612

MED21

0.609

ZBTB24

0.607

KIAA0355

0.574

EED

0.516

GABPA

0.500

GMEB1

0.491

PEX7

0.490

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EED	MED21	ENSCAFP00000006672	ENSCAFP00000052409	Embryonic ectoderm development.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.480
EED	MED30	ENSCAFP00000006672	ENSCAFP00000001180	Embryonic ectoderm development.	Mediator complex subunit 30.	0.561
EED	PKNOX1	ENSCAFP00000006672	ENSCAFP00000015472	Embryonic ectoderm development.	PBX/knotted 1 homeobox 1.	0.516
GABPA	PKNOX1	ENSCAFP00000012511	ENSCAFP00000015472	GA binding protein transcription factor subunit alpha.	PBX/knotted 1 homeobox 1.	0.500
GMEB1	PKNOX1	ENSCAFP00000017230	ENSCAFP00000015472	Glucocorticoid modulatory element binding protein 1.	PBX/knotted 1 homeobox 1.	0.491
KIAA0355	PKNOX1	ENSCAFP00000010894	ENSCAFP00000015472	KIAA0355.	PBX/knotted 1 homeobox 1.	0.574
MED21	EED	ENSCAFP00000052409	ENSCAFP00000006672	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Embryonic ectoderm development.	0.480
MED21	MED30	ENSCAFP00000052409	ENSCAFP00000001180	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator complex subunit 30.	0.967
MED21	PEX7	ENSCAFP00000052409	ENSCAFP00000000364	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisomal biogenesis factor 7.	0.494
MED21	PKNOX1	ENSCAFP00000052409	ENSCAFP00000015472	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	PBX/knotted 1 homeobox 1.	0.609
MED30	EED	ENSCAFP00000001180	ENSCAFP00000006672	Mediator complex subunit 30.	Embryonic ectoderm development.	0.561
MED30	MED21	ENSCAFP00000001180	ENSCAFP00000052409	Mediator complex subunit 30.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.967
MED30	PEX7	ENSCAFP00000001180	ENSCAFP00000000364	Mediator complex subunit 30.	Peroxisomal biogenesis factor 7.	0.590
MED30	PKNOX1	ENSCAFP00000001180	ENSCAFP00000015472	Mediator complex subunit 30.	PBX/knotted 1 homeobox 1.	0.657
MYBBP1A	PBX4	ENSCAFP00000036879	ENSCAFP00000019597	MYB binding protein 1a.	PBX homeobox 4.	0.858
MYBBP1A	PKNOX1	ENSCAFP00000036879	ENSCAFP00000015472	MYB binding protein 1a.	PBX/knotted 1 homeobox 1.	0.725
PBX4	MYBBP1A	ENSCAFP00000019597	ENSCAFP00000036879	PBX homeobox 4.	MYB binding protein 1a.	0.858
PBX4	PKNOX1	ENSCAFP00000019597	ENSCAFP00000015472	PBX homeobox 4.	PBX/knotted 1 homeobox 1.	0.612
PEX7	MED21	ENSCAFP00000000364	ENSCAFP00000052409	Peroxisomal biogenesis factor 7.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.494
PEX7	MED30	ENSCAFP00000000364	ENSCAFP00000001180	Peroxisomal biogenesis factor 7.	Mediator complex subunit 30.	0.590