STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (913 aa)    
Predicted Functional Partners:
FBXL7
F-box and leucine rich repeat protein 7.
   
  
 0.707
CORIN
Corin, serine peptidase.
   
 
 0.697
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
 
 
 
 0.695
ZNF184
Zinc finger protein 184.
    
 
 0.679
ARMC10
Armadillo repeat containing 10.
   
 
 0.653
MBTPS1
Membrane bound transcription factor peptidase, site 1.
      
 0.646
METTL1
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
     
 0.630
TM2D3
TM2 domain containing 3.
      
 0.629
QRICH2
Glutamine rich 2.
   
 
 0.613
SCG5
Secretogranin V.
   
 
 0.610
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.