STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UCHL5Ubiquitin carboxyl-terminal hydrolase. (328 aa)    
Predicted Functional Partners:
USP14
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.987
PSMD14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.970
ACTR5
Actin related protein 5; Belongs to the actin family.
    
 0.969
NFRKB
Nuclear factor related to kappaB binding protein.
    
 0.968
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.967
RPS9
TCF3 fusion partner.
   
 0.965
INO80C
INO80 complex subunit C.
    
 0.954
PSMD13
Proteasome 26S subunit, non-ATPase 13.
   
 
 0.954
PSMC2
Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.
   
 
 0.953
INO80
INO80 complex ATPase subunit.
    
 0.953
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.