STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRB14Growth factor receptor bound protein 14. (162 aa)    
Predicted Functional Partners:
GRB14-2
Uncharacterized protein.
 
      0.900
INSR
Tyrosine-protein kinase receptor.
    
 0.896
IGF1R
Tyrosine-protein kinase receptor.
    
 0.762
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.630
GTF3A
General transcription factor IIIA.
    
 
 0.614
FAIM2
Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family.
      
 0.592
TMEM160
Transmembrane protein 160.
   
  
 0.591
INSRR
Tyrosine-protein kinase receptor.
    
 0.576
DGKG
Diacylglycerol kinase.
      
 0.575
CARD9
Caspase recruitment domain family member 9.
      
 0.547
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.