STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORCS3Sortilin related VPS10 domain containing receptor 3. (1206 aa)    
Predicted Functional Partners:
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.777
CFDP1
Craniofacial development protein 1; May play a role during embryogenesis.
      
 0.738
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
   
  
 0.670
STK33
Serine/threonine kinase 33.
   
  
 0.652
SLC39A12
Solute carrier family 39 member 12.
   
  
 0.639
NGF
Nerve growth factor; Belongs to the NGF-beta family.
   
 
 0.610
OLFM3
Olfactomedin 3.
   
  
 0.610
ENPP5
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5.
      
 0.592
CNKSR3
Uncharacterized protein.
      
 0.588
NTS
Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
    
 
 0.565
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.