STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORCS3Sortilin related VPS10 domain containing receptor 3. (1206 aa)    
Predicted Functional Partners:
SORT1
Sortilin.
    
 0.836
ZNF511
Zinc finger protein 511.
      
 0.810
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.653
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
   
  
 0.623
NGF
Nerve growth factor; Belongs to the NGF-beta family.
    
 
 0.613
DGKB
Diacylglycerol kinase.
   
  
 0.605
CNTNAP5
Contactin-associated protein-like 5; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication; Belongs to the neurexin family.
   
  
 0.604
OLFM3
Olfactomedin 3.
   
  
 0.604
STK33
Serine/threonine kinase 33.
   
  
 0.601
CFDP1
Craniofacial development protein 1; May play a role during embryogenesis.
      
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.