STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BICD1BICD cargo adaptor 1. (904 aa)    
Predicted Functional Partners:
BICD2
BICD cargo adaptor 2.
   
  0.965
EXD1
Exonuclease 3'-5' domain containing 1.
    
 
 0.827
DYNC1LI1
Dynein cytoplasmic 1 light intermediate chain 1.
    
 
 0.809
DCTN1
Dynactin subunit 1.
    
 
 0.779
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
    
 
 0.747
RANBP2
RAN binding protein 2.
    
 
 0.739
HOOK3
Hook microtubule tethering protein 3.
   
 
 0.730
DYNC1LI2
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 
 0.729
RAB6A
RAB6A, member RAS oncogene family.
    
 
 0.699
RAB6B
RAB6B, member RAS oncogene family.
    
 
 0.699
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.