STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BICD1BICD cargo adaptor 1. (904 aa)    
Predicted Functional Partners:
DYNC1LI1
Dynein cytoplasmic 1 light intermediate chain 1.
   
 0.869
DCTN1
Dynactin subunit 1.
   
 0.863
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
    
 0.860
RAB6A
RAB6A, member RAS oncogene family.
    
 0.856
RAB6B
RAB6B, member RAS oncogene family.
   
 0.856
DCTN2
Dynactin subunit 2.
    
 0.818
BICD2
BICD cargo adaptor 2.
  
0.802
DYNC1LI2
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 0.786
DYNC1I2
Dynein cytoplasmic 1 intermediate chain 2.
    
 0.762
DYNC1I1
Dynein cytoplasmic 1 intermediate chain 1.
    
  0.753
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.