STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTF3C3General transcription factor IIIC subunit 3. (883 aa)    
Predicted Functional Partners:
GTF3C4
General transcription factor IIIC subunit 4.
   
 0.998
GTF3C2
General transcription factor IIIC subunit 2.
   
 0.997
GTF3C1
General transcription factor IIIC subunit 1.
   
 0.997
BDP1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB.
   
 0.942
POLR3D
RNA polymerase III subunit D.
    
 0.913
BRF1
BRF1 RNA polymerase III transcription initiation factor subunit.
    
 
 0.883
BRF2
BRF2 RNA polymerase III transcription initiation factor subunit.
    
 0.838
SYMPK
Symplekin.
   
 
 0.811
POLR3A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.807
CPSF3
Cleavage and polyadenylation specific factor 3.
   
   0.783
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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