STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIREAutoimmune regulator. (583 aa)    
Predicted Functional Partners:
FOXN1
Forkhead box N1.
   
 
 0.818
GMEB1
Glucocorticoid modulatory element binding protein 1.
      
 0.659
CD80
CD80 molecule.
      
 0.646
FEZF2
FEZ family zinc finger 2.
   
 
 0.613
ZNF341
Zinc finger protein 341.
   
 
 0.609
HPS3
Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.
      
 0.574
GATAD2B
GATA zinc finger domain containing 2B.
   
 
 0.565
NYNRIN
NYN domain and retroviral integrase containing.
   
 
 0.564
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 
 0.560
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 
 0.558
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.