STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGHMBP2Immunoglobulin mu DNA binding protein 2. (1040 aa)    
Predicted Functional Partners:
ABT1
Activator of basal transcription 1.
   
 
 0.784
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
   
  
 0.762
DHTKD1
Dehydrogenase E1 and transketolase domain containing 1.
   
  
 0.660
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin.
   
  
 0.652
SLC52A1
Uncharacterized protein.
   
  
 0.610
SMN
Survival motor neuron protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the ch [...]
      
 0.586
BICD2
BICD cargo adaptor 2.
   
  
 0.581
CNTNAP1
Contactin associated protein 1.
   
  
 0.574
FIG4
FIG4 phosphoinositide 5-phosphatase.
      
 0.566
ZC4H2
Zinc finger C4H2-type containing.
   
  
 0.563
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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