STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGHMBP2Immunoglobulin mu DNA binding protein 2. (1040 aa)    
Predicted Functional Partners:
NELFE
Negative elongation factor complex member E.
    
 
 0.838
NELFA
Negative elongation factor complex member A.
   
   0.823
ABT1
Activator of basal transcription 1.
    
 
 0.779
GRSF1
G-rich RNA sequence binding factor 1.
    
   0.767
UQCC3
Ubiquinol-cytochrome c reductase complex assembly factor 3.
      
 0.691
LAS1L
LAS1 like, ribosome biogenesis factor.
      
 0.682
SMN
Survival motor neuron protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the ch [...]
      
 0.607
DHTKD1
Dehydrogenase E1 and transketolase domain containing 1.
   
  
 0.606
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
   
  
 0.594
SSH3
Slingshot protein phosphatase 3.
      
 0.584
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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