STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPNA6Importin subunit alpha; Functions in nuclear protein import. (536 aa)    
Predicted Functional Partners:
KPNA1
Importin subunit alpha; Functions in nuclear protein import.
   
  0.915
KPNB1
Karyopherin subunit beta 1.
   
 0.891
GMCL1
BTB domain-containing protein.
   
 
 0.853
ZBTB25
Zinc finger and BTB domain containing 25.
   
 
 0.850
CSE1L
Chromosome segregation 1 like.
   
 0.848
USHBP1
USH1 protein network component harmonin binding protein 1.
      
 0.812
KPNA3
Importin subunit alpha; Functions in nuclear protein import.
  
0.804
NUP50
Nucleoporin 50.
   
 
 0.735
KPNA4
Importin subunit alpha; Functions in nuclear protein import.
   
 0.717
NANS
N-acetylneuraminate synthase.
   
 
 0.705
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.