IPO8 protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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[Homology]

Score

IPO8

Importin 8. (1037 aa)

Predicted Functional Partners:

KPNB1

0.875

AGO2

0.857

LOC100686305

0.841

RANBP6

0.832

FAU

0.817

ENSCAFP00000054759

0.817

ENSCAFP00000061156

0.817

PES1

0.793

NUP93

0.782

NUP37

0.778

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	IPO8	ENSCAFP00000043303	ENSCAFP00000015868	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Importin 8.	0.857
AGO2	LOC100686305	ENSCAFP00000043303	ENSCAFP00000048537	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.577
AGO2	NUP37	ENSCAFP00000043303	ENSCAFP00000010802	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Nucleoporin 37.	0.424
AGO2	NUP93	ENSCAFP00000043303	ENSCAFP00000013384	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.	0.426
ENSCAFP00000054759	ENSCAFP00000061156	ENSCAFP00000054759	ENSCAFP00000061156	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.913
ENSCAFP00000054759	FAU	ENSCAFP00000054759	ENSCAFP00000033982	Ubiquitin-like domain-containing protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.912
ENSCAFP00000054759	IPO8	ENSCAFP00000054759	ENSCAFP00000015868	Ubiquitin-like domain-containing protein.	Importin 8.	0.817
ENSCAFP00000061156	ENSCAFP00000054759	ENSCAFP00000061156	ENSCAFP00000054759	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.913
ENSCAFP00000061156	FAU	ENSCAFP00000061156	ENSCAFP00000033982	Ubiquitin-like domain-containing protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.909
ENSCAFP00000061156	IPO8	ENSCAFP00000061156	ENSCAFP00000015868	Ubiquitin-like domain-containing protein.	Importin 8.	0.817
FAU	ENSCAFP00000054759	ENSCAFP00000033982	ENSCAFP00000054759	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like domain-containing protein.	0.912
FAU	ENSCAFP00000061156	ENSCAFP00000033982	ENSCAFP00000061156	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like domain-containing protein.	0.909
FAU	IPO8	ENSCAFP00000033982	ENSCAFP00000015868	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Importin 8.	0.817
IPO8	AGO2	ENSCAFP00000015868	ENSCAFP00000043303	Importin 8.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.857
IPO8	ENSCAFP00000054759	ENSCAFP00000015868	ENSCAFP00000054759	Importin 8.	Ubiquitin-like domain-containing protein.	0.817
IPO8	ENSCAFP00000061156	ENSCAFP00000015868	ENSCAFP00000061156	Importin 8.	Ubiquitin-like domain-containing protein.	0.817
IPO8	FAU	ENSCAFP00000015868	ENSCAFP00000033982	Importin 8.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.817
IPO8	KPNB1	ENSCAFP00000015868	ENSCAFP00000044873	Importin 8.	Karyopherin subunit beta 1.	0.875
IPO8	LOC100686305	ENSCAFP00000015868	ENSCAFP00000048537	Importin 8.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.841
IPO8	NUP37	ENSCAFP00000015868	ENSCAFP00000010802	Importin 8.	Nucleoporin 37.	0.778