STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISD2CDGSH iron sulfur domain 2. (135 aa)    
Predicted Functional Partners:
TIMM10
Translocase of inner mitochondrial membrane 10.
   
 
 0.792
BDH2
Uncharacterized protein.
   
  
 0.651
NDUFA8
NADH:ubiquinone oxidoreductase subunit A8.
   
 
 0.642
NDUFA13
NADH:ubiquinone oxidoreductase subunit A13.
   
 
 0.630
SLC39A8
Solute carrier family 39 member 8.
    
 
 0.605
HSD11B2
Hydroxysteroid 11-beta dehydrogenase 2.
      
 0.603
TACR3
Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family.
      
 0.598
SDHD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.
   
 
 0.564
BANK1
B cell scaffold protein with ankyrin repeats 1.
      
 0.563
ENSCAFP00000057514
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.
   
 
 0.563
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.