BDH2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

BDH2

Uncharacterized protein. (245 aa)

Predicted Functional Partners:

BDH1

0.883

OXCT1

0.845

HMGCL

0.802

LOC477430

0.752

PPP1R7

0.752

CISD2

0.635

HMGCLL1

0.625

HMGCS2

0.624

SLC9B2

0.619

UBE2D3

0.612

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDH1	BDH2	ENSCAFP00000050035	ENSCAFP00000015909	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein.	0.883
BDH1	HMGCL	ENSCAFP00000050035	ENSCAFP00000019305	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.961
BDH1	HMGCLL1	ENSCAFP00000050035	ENSCAFP00000055926	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.911
BDH1	HMGCS2	ENSCAFP00000050035	ENSCAFP00000014843	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.708
BDH1	OXCT1	ENSCAFP00000050035	ENSCAFP00000066198	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.968
BDH2	BDH1	ENSCAFP00000015909	ENSCAFP00000050035	Uncharacterized protein.	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.883
BDH2	CISD2	ENSCAFP00000015909	ENSCAFP00000015869	Uncharacterized protein.	CDGSH iron sulfur domain 2.	0.635
BDH2	HMGCL	ENSCAFP00000015909	ENSCAFP00000019305	Uncharacterized protein.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.802
BDH2	HMGCLL1	ENSCAFP00000015909	ENSCAFP00000055926	Uncharacterized protein.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.625
BDH2	HMGCS2	ENSCAFP00000015909	ENSCAFP00000014843	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.624
BDH2	LOC477430	ENSCAFP00000015909	ENSCAFP00000038534	Uncharacterized protein.	Uncharacterized protein.	0.752
BDH2	OXCT1	ENSCAFP00000015909	ENSCAFP00000066198	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.845
BDH2	PPP1R7	ENSCAFP00000015909	ENSCAFP00000059322	Uncharacterized protein.	Protein phosphatase 1 regulatory subunit 7.	0.752
BDH2	SLC9B2	ENSCAFP00000015909	ENSCAFP00000015896	Uncharacterized protein.	Solute carrier family 9 member B2.	0.619
BDH2	UBE2D3	ENSCAFP00000015909	ENSCAFP00000043478	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.612
CISD2	BDH2	ENSCAFP00000015869	ENSCAFP00000015909	CDGSH iron sulfur domain 2.	Uncharacterized protein.	0.635
CISD2	UBE2D3	ENSCAFP00000015869	ENSCAFP00000043478	CDGSH iron sulfur domain 2.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.532
HMGCL	BDH1	ENSCAFP00000019305	ENSCAFP00000050035	3-hydroxy-3-methylglutaryl-CoA lyase.	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.961
HMGCL	BDH2	ENSCAFP00000019305	ENSCAFP00000015909	3-hydroxy-3-methylglutaryl-CoA lyase.	Uncharacterized protein.	0.802
HMGCL	HMGCLL1	ENSCAFP00000019305	ENSCAFP00000055926	3-hydroxy-3-methylglutaryl-CoA lyase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.881