STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTP4A2Protein tyrosine phosphatase 4A2. (167 aa)    
Predicted Functional Partners:
RABGGTB
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.911
ARL15
ADP ribosylation factor like GTPase 15.
   
 
 0.643
MBLAC2
Metallo-beta-lactamase domain containing 2.
    
 
 0.553
MTDH
Metadherin.
   
  
 0.539
CNNM3
Cyclin and CBS domain divalent metal cation transport mediator 4.
    
 
 0.530
KRR1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
      
 0.517
FKBP15
Peptidylprolyl isomerase.
   
  
 0.516
TRPC4AP
Transient receptor potential cation channel subfamily C member 4 associated protein.
   
  
 0.516
TM2D2
TM2 domain containing 2.
   
  
 0.516
FBXL12
F-box and leucine rich repeat protein 12.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.