STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPP6R3Protein phosphatase 6 regulatory subunit 3. (897 aa)    
Predicted Functional Partners:
ANKRD28
Ankyrin repeat domain 28.
   
 0.934
PPP6C
Serine/threonine-protein phosphatase.
   
 0.856
ANKRD52
Ankyrin repeat domain 52.
    
 
 0.777
PPP6R1
Protein phosphatase 6 regulatory subunit 1.
   
 
 0.729
PPP6C-2
Protein phosphatase 6 catalytic subunit.
   
 
 0.699
PLK1
Serine/threonine-protein kinase PLK.
    
 
 0.674
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
   0.646
ANKRD44
Ankyrin repeat domain 44.
   
 
 0.610
DYM
Dymeclin.
   
  
 0.564
CCDC158
Coiled-coil domain containing 158.
      
 0.555
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.