TACR3 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TACR3

Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa)

Predicted Functional Partners:

KISS1

0.881

TAC1

0.863

GNRH1

0.766

GNB3

0.722

OXT

0.718

GNAQ

0.674

GNA14

0.674

GNA11

0.674

CNKSR3

0.641

NTS

0.640

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNKSR3	TACR3	ENSCAFP00000065573	ENSCAFP00000015974	Uncharacterized protein.	Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.641
GNA11	GNA14	ENSCAFP00000050168	ENSCAFP00000041847	Uncharacterized protein.	G protein subunit alpha 14.	0.903
GNA11	GNAQ	ENSCAFP00000050168	ENSCAFP00000028446	Uncharacterized protein.	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.909
GNA11	GNB3	ENSCAFP00000050168	ENSCAFP00000058821	Uncharacterized protein.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.701
GNA11	TACR3	ENSCAFP00000050168	ENSCAFP00000015974	Uncharacterized protein.	Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.674
GNA14	GNA11	ENSCAFP00000041847	ENSCAFP00000050168	G protein subunit alpha 14.	Uncharacterized protein.	0.903
GNA14	GNAQ	ENSCAFP00000041847	ENSCAFP00000028446	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.903
GNA14	GNB3	ENSCAFP00000041847	ENSCAFP00000058821	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.881
GNA14	GNRH1	ENSCAFP00000041847	ENSCAFP00000013198	G protein subunit alpha 14.	Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.	0.535
GNA14	KISS1	ENSCAFP00000041847	ENSCAFP00000037810	G protein subunit alpha 14.	Kisspeptin.	0.528
GNA14	NTS	ENSCAFP00000041847	ENSCAFP00000008959	G protein subunit alpha 14.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.536
GNA14	OXT	ENSCAFP00000041847	ENSCAFP00000048730	G protein subunit alpha 14.	Oxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family.	0.548
GNA14	TAC1	ENSCAFP00000041847	ENSCAFP00000003217	G protein subunit alpha 14.	Tachykinin precursor 1.	0.539
GNA14	TACR3	ENSCAFP00000041847	ENSCAFP00000015974	G protein subunit alpha 14.	Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.674
GNAQ	GNA11	ENSCAFP00000028446	ENSCAFP00000050168	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Uncharacterized protein.	0.909
GNAQ	GNA14	ENSCAFP00000028446	ENSCAFP00000041847	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	G protein subunit alpha 14.	0.903
GNAQ	GNB3	ENSCAFP00000028446	ENSCAFP00000058821	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.844
GNAQ	GNRH1	ENSCAFP00000028446	ENSCAFP00000013198	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.	0.559
GNAQ	KISS1	ENSCAFP00000028446	ENSCAFP00000037810	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Kisspeptin.	0.543
GNAQ	NTS	ENSCAFP00000028446	ENSCAFP00000008959	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.536