STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF38Rho guanine nucleotide exchange factor 38. (777 aa)    
Predicted Functional Partners:
ARHGAP9
SH3 domain-containing protein.
    
 
 0.889
IFRD2
Interferon related developmental regulator 2.
      
 0.735
ARHGEF16
Rho guanine nucleotide exchange factor 16.
   
  
 0.680
ARHGEF19
Rho guanine nucleotide exchange factor 19.
      
 0.677
AMPH
Amphiphysin.
   
 
 0.665
BIN1
Bridging integrator 1.
   
 
 0.663
BIN2
Bridging integrator 2.
    
 
 0.662
FARP2
FERM, ARH/RhoGEF and pleckstrin domain protein 2.
   
  
0.640
FGD6
FYVE, RhoGEF and PH domain containing 6.
      
 0.637
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
   
  
 0.637
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.