STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP72Centrosomal protein 72. (626 aa)    
Predicted Functional Partners:
PCM1
Pericentriolar material 1.
    
 
 0.952
CCDC14
Coiled-coil domain containing 14.
    
 
 0.851
CEP131
Centrosomal protein 131.
    
 
 0.832
CEP290
Centrosomal protein 290.
    
 
 0.805
CCDC66
Coiled-coil domain-containing protein 66; Microtubule-binding protein required for ciliogenesis. May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites (By similarity). Plays a role in retina morphogenesis and/or homeostasis.
      
 0.717
TACC3
Transforming acidic coiled-coil containing protein 3.
   
 
 0.695
ZC3H15
Zinc finger CCCH-type containing 15.
      
 0.687
EIF1AD
Eukaryotic translation initiation factor 1A domain containing.
      
 0.681
WDR74
WD repeat domain 74.
      
 0.672
TSR2
G protein nucleolar 3 like.
      
 0.655
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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