STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTN2Actinin alpha 2. (894 aa)    
Predicted Functional Partners:
ACTN3
Actinin alpha 3.
  
0.999
MYOZ1
Calsarcin 2.
   
 
 0.935
CSRP3
Cysteine and glycine rich protein 3.
   
 0.919
MYOZ2
Myozenin 2.
   
 
 0.906
VCL
Vinculin.
   
 0.904
TNNI1
Troponin I1, slow skeletal type.
   
 
 0.894
ACTN1
Actinin alpha 1.
  
0.893
TCAP
Titin-cap.
   
 
 0.884
MYBPC3
Myosin binding protein C, cardiac.
   
 0.855
TNNI3
Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
   
 0.851
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.