STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EI24EI24 autophagy associated transmembrane protein. (340 aa)    
Predicted Functional Partners:
TP53I3
Tumor protein p53 inducible protein 3.
     
 0.886
TTC37
Tetratricopeptide repeat domain 37.
      
 0.692
TP53BP1
Tumor protein p53 binding protein 1.
      
 0.623
CRYZ
PKS_ER domain-containing protein.
     
 0.600
ENSCAFP00000061033
PKS_ER domain-containing protein.
     
 0.600
EPG5
Ectopic P-granules autophagy protein 5 homolog.
      
 0.537
PERP
P53 apoptosis effector related to PMP22.
      
 0.530
VMP1
Vacuole membrane protein 1.
      
 0.529
AEN
Apoptosis enhancing nuclease.
      
 0.524
STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation [...]
 
 
    0.484
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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