FMO5 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FMO5

Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)

Predicted Functional Partners:

CYP2D15

0.813

ACP6

0.799

GGT6

0.786

GAD2

0.785

GSS

0.785

LOC481634

0.780

GGT5

0.780

GGT1

0.774

CSAD

0.731

GADL1

0.731

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACP6	FMO5	ENSCAFP00000061309	ENSCAFP00000016038	Acid phosphatase 6, lysophosphatidic; Belongs to the histidine acid phosphatase family.	Dimethylaniline monooxygenase [N-oxide-forming].	0.799
CSAD	FMO5	ENSCAFP00000010512	ENSCAFP00000016038	Cysteine sulfinic acid decarboxylase.	Dimethylaniline monooxygenase [N-oxide-forming].	0.731
CSAD	GAD2	ENSCAFP00000010512	ENSCAFP00000006413	Cysteine sulfinic acid decarboxylase.	Glutamate decarboxylase 2; Catalyzes the production of GABA.	0.715
CSAD	GADL1	ENSCAFP00000010512	ENSCAFP00000048762	Cysteine sulfinic acid decarboxylase.	Glutamate decarboxylase like 1.	0.805
CSAD	GGT1	ENSCAFP00000010512	ENSCAFP00000055778	Cysteine sulfinic acid decarboxylase.	Uncharacterized protein.	0.821
CSAD	GGT5	ENSCAFP00000010512	ENSCAFP00000035912	Cysteine sulfinic acid decarboxylase.	Uncharacterized protein.	0.846
CSAD	GGT6	ENSCAFP00000010512	ENSCAFP00000022531	Cysteine sulfinic acid decarboxylase.	Gamma-glutamyltransferase 6.	0.800
CSAD	GSS	ENSCAFP00000010512	ENSCAFP00000011267	Cysteine sulfinic acid decarboxylase.	Glutathione synthetase.	0.825
CSAD	LOC481634	ENSCAFP00000010512	ENSCAFP00000003764	Cysteine sulfinic acid decarboxylase.	Uncharacterized protein.	0.848
CYP2D15	FMO5	ENSCAFP00000065572	ENSCAFP00000016038	Cytochrome P450 2D15; High activity for the hydroxylation of bunitrolol and imipramine; low activity on debrisoquine.	Dimethylaniline monooxygenase [N-oxide-forming].	0.813
FMO5	ACP6	ENSCAFP00000016038	ENSCAFP00000061309	Dimethylaniline monooxygenase [N-oxide-forming].	Acid phosphatase 6, lysophosphatidic; Belongs to the histidine acid phosphatase family.	0.799
FMO5	CSAD	ENSCAFP00000016038	ENSCAFP00000010512	Dimethylaniline monooxygenase [N-oxide-forming].	Cysteine sulfinic acid decarboxylase.	0.731
FMO5	CYP2D15	ENSCAFP00000016038	ENSCAFP00000065572	Dimethylaniline monooxygenase [N-oxide-forming].	Cytochrome P450 2D15; High activity for the hydroxylation of bunitrolol and imipramine; low activity on debrisoquine.	0.813
FMO5	GAD2	ENSCAFP00000016038	ENSCAFP00000006413	Dimethylaniline monooxygenase [N-oxide-forming].	Glutamate decarboxylase 2; Catalyzes the production of GABA.	0.785
FMO5	GADL1	ENSCAFP00000016038	ENSCAFP00000048762	Dimethylaniline monooxygenase [N-oxide-forming].	Glutamate decarboxylase like 1.	0.731
FMO5	GGT1	ENSCAFP00000016038	ENSCAFP00000055778	Dimethylaniline monooxygenase [N-oxide-forming].	Uncharacterized protein.	0.774
FMO5	GGT5	ENSCAFP00000016038	ENSCAFP00000035912	Dimethylaniline monooxygenase [N-oxide-forming].	Uncharacterized protein.	0.780
FMO5	GGT6	ENSCAFP00000016038	ENSCAFP00000022531	Dimethylaniline monooxygenase [N-oxide-forming].	Gamma-glutamyltransferase 6.	0.786
FMO5	GSS	ENSCAFP00000016038	ENSCAFP00000011267	Dimethylaniline monooxygenase [N-oxide-forming].	Glutathione synthetase.	0.785
FMO5	LOC481634	ENSCAFP00000016038	ENSCAFP00000003764	Dimethylaniline monooxygenase [N-oxide-forming].	Uncharacterized protein.	0.780