Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXN4Forkhead box N4. (523 aa)    
Predicted Functional Partners:
FOXJ1
Forkhead box J1.
   
  
 0.934
FOXN1
Forkhead box N1.
   
  
 0.933
CCDC177
Coiled-coil domain containing 177.
    
 
 0.893
HRCT1
Histidine rich carboxyl terminus 1.
      
 0.867
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B.
    
 
 0.777
SLC37A4
MFS domain-containing protein.
      
 0.688
SP1
Sp1 transcription factor.
    
 
 0.643
FOXN2
Forkhead box N2.
   
  
 0.618
TWIST2
Twist family bHLH transcription factor 2.
   
  
 0.617
ESX1
ESX homeobox 1.
   
 
 0.611
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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