STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKNOX2PBX/knotted 1 homeobox 2. (472 aa)    
Predicted Functional Partners:
FNBP1
Formin binding protein 1.
      
 0.828
FLOT2
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
   
  
 0.812
ABRACL
ABRA C-terminal like.
      
 0.799
DDX25
DEAD-box helicase 25.
   
  
 0.624
SORCS2
Sortilin related VPS10 domain containing receptor 2.
   
  
 0.624
HYLS1
HYLS1 centriolar and ciliogenesis associated.
      
 0.614
LMX1A
LIM homeobox transcription factor 1 alpha.
    
 
 0.606
LMX1B
LIM homeobox transcription factor 1 beta.
    
 
 0.606
HOXB1
Homeobox B1.
   
 
 0.602
AKAP12
A-kinase anchoring protein 12.
      
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.