STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H1-6H15 domain-containing protein. (294 aa)    
Predicted Functional Partners:
H1-8
H15 domain-containing protein.
   
 
 0.911
LRWD1
Leucine rich repeats and WD repeat domain containing 1.
      
 0.852
MTIF3
Mitochondrial translational initiation factor 3.
      
 0.688
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 
 0.616
NAP1L4
Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family.
    
 
 0.611
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.605
TNP2
Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
      
 0.532
RBFA
Uncharacterized protein.
      
 0.515
CCNE1
Cyclin E1; Belongs to the cyclin family.
    
 
 0.512
IMMP1L
Mitochondrial inner membrane protease subunit.
      
 0.512
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.