STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFTN2Raftlin family member 2. (507 aa)    
Predicted Functional Partners:
ARL6IP6
ADP ribosylation factor like GTPase 6 interacting protein 6.
      
 0.891
PLBD2
Phospholipase B-like; Putative phospholipase.
      
 0.889
N6AMT1
N-6 adenine-specific DNA methyltransferase 1.
      
 0.879
NUGGC
Nuclear GTPase, germinal center associated.
      
 0.635
AKAP6
A-kinase anchoring protein 6.
      
 0.515
RGS13
Regulator of G protein signaling 13.
      
 0.491
TNFSF8
Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.
      
 0.485
MS4A1
B-lymphocyte antigen CD20; B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
      
 0.485
AKAP14
Uncharacterized protein.
      
 0.482
CLGN
Calmegin; Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity).
      
 0.480
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.