STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIMMDC1Translocase of inner mitochondrial membrane domain containing 1. (279 aa)    
Predicted Functional Partners:
NDUFAF4
NADH:ubiquinone oxidoreductase complex assembly factor 4.
   
 
 0.979
NDUFAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
   
 
 0.974
TMEM126B
Transmembrane protein 126B.
   
 
 0.970
NDUFA8
NADH:ubiquinone oxidoreductase subunit A8.
   
 
 0.968
ACAD9
Acyl-CoA dehydrogenase family member 9.
   
 
 0.964
ECSIT
ECSIT signalling integrator.
   
 
 0.961
NDUFA12
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 
 0.960
NDUFA13
NADH:ubiquinone oxidoreductase subunit A13.
    
 
 0.960
NDUFS2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
   
 
 0.960
NDUFB10
NADH:ubiquinone oxidoreductase subunit B10.
   
 
 0.953
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.