STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEPACAMHepatic and glial cell adhesion molecule. (418 aa)    
Predicted Functional Partners:
SERPINB12
Serpin family B member 12; Belongs to the serpin family.
      
 0.769
SBSN
Uncharacterized protein.
      
 0.697
CASP14
Caspase 14; Belongs to the peptidase C14A family.
      
 0.636
PNLIPRP3
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
      
 0.636
PRDX6
Peroxiredoxin 6.
      
 0.621
DNMT3A
DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.564
KRTDAP
Keratinocyte differentiation-associated protein; May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis (By similarity).
      
 0.515
MADD
MAP kinase activating death domain.
      
 0.515
TP53TG5
TP53 target 5.
   
  
 0.497
SH2D4B
SH2 domain containing 4B.
   
  
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.