STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDCD6Programmed cell death 6. (187 aa)    
Predicted Functional Partners:
SEC31A
SEC31 homolog A, COPII coat complex component.
   
 0.833
PDCD6IP
Programmed cell death 6 interacting protein.
    
 
 0.775
KLHL12
Adiponectin receptor 1.
    
 
 0.766
SEC31B
SEC31 homolog B, COPII coat complex component.
    
 0.757
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
   
 0.688
ANXA11
Annexin.
   
 
 0.636
SEC23IP
SEC23 interacting protein.
    
 
 0.621
HEBP2
Heme binding protein 2.
   
 
 0.609
SAR1B
Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.
   
 0.531
TSG101
Tumor susceptibility 101.
   
 
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.