STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC127Coiled-coil domain containing 127. (479 aa)    
Predicted Functional Partners:
AP1AR
Adaptor related protein complex 1 associated regulatory protein.
    
   0.926
ATP6V1FNB
ATP6V1F neighbor.
      
 0.829
CFAP61
Cilia and flagella associated protein 61.
      
 0.820
C6orf58
Chromosome 6 open reading frame 58.
      
 0.810
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
      
 0.810
MTO1
Mitochondrial tRNA translation optimization 1.
      
 0.772
CSNK2A2
Casein kinase 2 alpha 2.
      
 0.753
CST11
Cystatin 11.
      
 0.751
XPNPEP1
X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.
      
 0.749
AARS1
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
      
 0.746
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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