BCL9 protein (Canis lupus familiaris) - STRING interaction network

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Score

BCL9

BCL9 transcription coactivator. (1426 aa)

Predicted Functional Partners:

CTNNB1

0.981

LEF1

0.950

TCF7L1

0.940

TCF7

0.928

BCL9L

0.909

CDC73

0.693

JUP

0.671

TCF7L2

0.609

PYGO1

0.579

LOC612779

0.548

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL9	BCL9L	ENSCAFP00000016276	ENSCAFP00000054160	BCL9 transcription coactivator.	BCL9 like.	0.909
BCL9	CDC73	ENSCAFP00000016276	ENSCAFP00000061651	BCL9 transcription coactivator.	Cell division cycle 73.	0.693
BCL9	CTNNB1	ENSCAFP00000016276	ENSCAFP00000007783	BCL9 transcription coactivator.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.981
BCL9	JUP	ENSCAFP00000016276	ENSCAFP00000023403	BCL9 transcription coactivator.	Uncharacterized protein.	0.671
BCL9	LEF1	ENSCAFP00000016276	ENSCAFP00000056485	BCL9 transcription coactivator.	Lymphoid enhancer binding factor 1.	0.950
BCL9	LOC612779	ENSCAFP00000016276	ENSCAFP00000040000	BCL9 transcription coactivator.	Histone H3; Belongs to the histone H3 family.	0.548
BCL9	PYGO1	ENSCAFP00000016276	ENSCAFP00000023436	BCL9 transcription coactivator.	Pygopus family PHD finger 1.	0.579
BCL9	TCF7	ENSCAFP00000016276	ENSCAFP00000043629	BCL9 transcription coactivator.	Transcription factor 7.	0.928
BCL9	TCF7L1	ENSCAFP00000016276	ENSCAFP00000011603	BCL9 transcription coactivator.	Transcription factor 7 like 1.	0.940
BCL9	TCF7L2	ENSCAFP00000016276	ENSCAFP00000039879	BCL9 transcription coactivator.	Transcription factor 7 like 2.	0.609
BCL9L	BCL9	ENSCAFP00000054160	ENSCAFP00000016276	BCL9 like.	BCL9 transcription coactivator.	0.909
BCL9L	CTNNB1	ENSCAFP00000054160	ENSCAFP00000007783	BCL9 like.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.784
BCL9L	LEF1	ENSCAFP00000054160	ENSCAFP00000056485	BCL9 like.	Lymphoid enhancer binding factor 1.	0.909
BCL9L	LOC612779	ENSCAFP00000054160	ENSCAFP00000040000	BCL9 like.	Histone H3; Belongs to the histone H3 family.	0.500
BCL9L	PYGO1	ENSCAFP00000054160	ENSCAFP00000023436	BCL9 like.	Pygopus family PHD finger 1.	0.849
BCL9L	TCF7	ENSCAFP00000054160	ENSCAFP00000043629	BCL9 like.	Transcription factor 7.	0.913
BCL9L	TCF7L1	ENSCAFP00000054160	ENSCAFP00000011603	BCL9 like.	Transcription factor 7 like 1.	0.903
CDC73	BCL9	ENSCAFP00000061651	ENSCAFP00000016276	Cell division cycle 73.	BCL9 transcription coactivator.	0.693
CDC73	CTNNB1	ENSCAFP00000061651	ENSCAFP00000007783	Cell division cycle 73.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.829
CDC73	JUP	ENSCAFP00000061651	ENSCAFP00000023403	Cell division cycle 73.	Uncharacterized protein.	0.593