BCL9 protein (Canis lupus familiaris) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

BCL9

BCL9 transcription coactivator. (1426 aa)

Predicted Functional Partners:

CTNNB1

0.940

TCF7L2

0.866

TCF7L1

0.792

LEF1

0.759

JUP

0.724

TCF7

0.683

PYGO1

0.630

BCL9L

0.592

LOC612779

0.553

LOC111090006

0.553

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL9	BCL9L	ENSCAFP00000016276	ENSCAFP00000054160	BCL9 transcription coactivator.	BCL9 like.	0.592
BCL9	CTNNB1	ENSCAFP00000016276	ENSCAFP00000007783	BCL9 transcription coactivator.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.940
BCL9	JUP	ENSCAFP00000016276	ENSCAFP00000023403	BCL9 transcription coactivator.	Uncharacterized protein.	0.724
BCL9	LEF1	ENSCAFP00000016276	ENSCAFP00000056485	BCL9 transcription coactivator.	Lymphoid enhancer binding factor 1.	0.759
BCL9	LOC111090006	ENSCAFP00000016276	ENSCAFP00000041760	BCL9 transcription coactivator.	Histone H3; Belongs to the histone H3 family.	0.553
BCL9	LOC612779	ENSCAFP00000016276	ENSCAFP00000040000	BCL9 transcription coactivator.	Histone H3; Belongs to the histone H3 family.	0.553
BCL9	PYGO1	ENSCAFP00000016276	ENSCAFP00000023436	BCL9 transcription coactivator.	Pygopus family PHD finger 1.	0.630
BCL9	TCF7	ENSCAFP00000016276	ENSCAFP00000043629	BCL9 transcription coactivator.	Transcription factor 7.	0.683
BCL9	TCF7L1	ENSCAFP00000016276	ENSCAFP00000011603	BCL9 transcription coactivator.	Transcription factor 7 like 1.	0.792
BCL9	TCF7L2	ENSCAFP00000016276	ENSCAFP00000039879	BCL9 transcription coactivator.	Transcription factor 7 like 2.	0.866
BCL9L	BCL9	ENSCAFP00000054160	ENSCAFP00000016276	BCL9 like.	BCL9 transcription coactivator.	0.592
BCL9L	CTNNB1	ENSCAFP00000054160	ENSCAFP00000007783	BCL9 like.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.524
BCL9L	LEF1	ENSCAFP00000054160	ENSCAFP00000056485	BCL9 like.	Lymphoid enhancer binding factor 1.	0.586
BCL9L	LOC111090006	ENSCAFP00000054160	ENSCAFP00000041760	BCL9 like.	Histone H3; Belongs to the histone H3 family.	0.499
BCL9L	LOC612779	ENSCAFP00000054160	ENSCAFP00000040000	BCL9 like.	Histone H3; Belongs to the histone H3 family.	0.499
BCL9L	PYGO1	ENSCAFP00000054160	ENSCAFP00000023436	BCL9 like.	Pygopus family PHD finger 1.	0.894
BCL9L	TCF7	ENSCAFP00000054160	ENSCAFP00000043629	BCL9 like.	Transcription factor 7.	0.541
BCL9L	TCF7L1	ENSCAFP00000054160	ENSCAFP00000011603	BCL9 like.	Transcription factor 7 like 1.	0.528
BCL9L	TCF7L2	ENSCAFP00000054160	ENSCAFP00000039879	BCL9 like.	Transcription factor 7 like 2.	0.532
CTNNB1	BCL9	ENSCAFP00000007783	ENSCAFP00000016276	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	BCL9 transcription coactivator.	0.940