STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROBO4Roundabout guidance receptor 4. (1043 aa)    
Predicted Functional Partners:
SLIT2
Slit guidance ligand 2.
   
 0.986
DIPK2B
Divergent protein kinase domain 2B.
   
  
 0.967
SLIT3
Slit guidance ligand 3.
   
 0.963
SLIT1
Slit guidance ligand 1.
   
 0.961
ABL1
Tyrosine-protein kinase.
   
 0.747
ABL2
Tyrosine-protein kinase.
   
 0.747
ROBO3
Roundabout guidance receptor 3.
    
 0.711
NCK2
Cytoplasmic protein.
    
 0.706
CLEC14A
C-type lectin domain containing 14A.
  
  
 0.701
NYX
Nyctalopin.
   
 0.698
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.