TRAIP protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

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[Homology]

Score

TRAIP

TRAF interacting protein. (469 aa)

Predicted Functional Partners:

PCNA

0.836

MAPRE2

0.821

DFFA

0.811

LRR1

0.768

FANCD2

0.728

TRAF3

0.724

NEIL3

0.720

TRAF2

0.711

TRAF1

0.711

CDC45

0.670

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC45	FANCD2	ENSCAFP00000021510	ENSCAFP00000040012	Cell division cycle 45.	FA complementation group D2.	0.650
CDC45	LRR1	ENSCAFP00000021510	ENSCAFP00000020889	Cell division cycle 45.	Leucine rich repeat protein 1.	0.587
CDC45	NEIL3	ENSCAFP00000021510	ENSCAFP00000041964	Cell division cycle 45.	Nei like DNA glycosylase 3.	0.436
CDC45	PCNA	ENSCAFP00000021510	ENSCAFP00000009045	Cell division cycle 45.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.887
CDC45	TRAIP	ENSCAFP00000021510	ENSCAFP00000016303	Cell division cycle 45.	TRAF interacting protein.	0.670
DFFA	TRAIP	ENSCAFP00000024677	ENSCAFP00000016303	DNA fragmentation factor subunit alpha.	TRAF interacting protein.	0.811
FANCD2	CDC45	ENSCAFP00000040012	ENSCAFP00000021510	FA complementation group D2.	Cell division cycle 45.	0.650
FANCD2	NEIL3	ENSCAFP00000040012	ENSCAFP00000041964	FA complementation group D2.	Nei like DNA glycosylase 3.	0.616
FANCD2	PCNA	ENSCAFP00000040012	ENSCAFP00000009045	FA complementation group D2.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.891
FANCD2	TRAIP	ENSCAFP00000040012	ENSCAFP00000016303	FA complementation group D2.	TRAF interacting protein.	0.728
LRR1	CDC45	ENSCAFP00000020889	ENSCAFP00000021510	Leucine rich repeat protein 1.	Cell division cycle 45.	0.587
LRR1	TRAIP	ENSCAFP00000020889	ENSCAFP00000016303	Leucine rich repeat protein 1.	TRAF interacting protein.	0.768
MAPRE2	TRAIP	ENSCAFP00000057698	ENSCAFP00000016303	Microtubule associated protein RP/EB family member 2.	TRAF interacting protein.	0.821
NEIL3	CDC45	ENSCAFP00000041964	ENSCAFP00000021510	Nei like DNA glycosylase 3.	Cell division cycle 45.	0.436
NEIL3	FANCD2	ENSCAFP00000041964	ENSCAFP00000040012	Nei like DNA glycosylase 3.	FA complementation group D2.	0.616
NEIL3	PCNA	ENSCAFP00000041964	ENSCAFP00000009045	Nei like DNA glycosylase 3.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.407
NEIL3	TRAIP	ENSCAFP00000041964	ENSCAFP00000016303	Nei like DNA glycosylase 3.	TRAF interacting protein.	0.720
PCNA	CDC45	ENSCAFP00000009045	ENSCAFP00000021510	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Cell division cycle 45.	0.887
PCNA	FANCD2	ENSCAFP00000009045	ENSCAFP00000040012	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	FA complementation group D2.	0.891
PCNA	NEIL3	ENSCAFP00000009045	ENSCAFP00000041964	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Nei like DNA glycosylase 3.	0.407