STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMZ2Archaelysin family metallopeptidase 2. (360 aa)    
Predicted Functional Partners:
ENSCAFP00000055086
Uncharacterized protein.
      
 0.566
CDH20
Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.561
TMEM214
Transmembrane protein 214.
      
 0.561
THBS2
Thrombospondin 2.
   
  
 0.545
DFFB
DNA fragmentation factor subunit beta.
   
  
 0.529
HSDL1
Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.517
ABITRAM
Actin binding transcription modulator.
   
  
 0.517
SPRYD7
SPRY domain containing 7.
      
 0.515
GTF2F2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
   
  
 0.515
PDZD3
PDZ domain containing 3.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.