close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (621 aa)    
Predicted Functional Partners:
SMCO2
Single-pass membrane protein with coiled-coil domains 2.
      
 0.793
CRY2
Cryptochrome circadian regulator 2.
   
 
 0.771
CRY1
Cryptochrome circadian regulator 1.
   
 
 0.734
CIPC
CLOCK interacting pacemaker.
    
 
 0.692
NPAS2
Neuronal PAS domain protein 2.
  
 
0.690
PASD1
PAS domain containing repressor 1.
   
 
 0.660
CLOCK
Clock circadian regulator.
   
 
0.660
CIART
Circadian associated repressor of transcription.
    
 
 0.627
NPAS4
Neuronal PAS domain protein 4.
    
 
0.608
DBP
D-box binding PAR bZIP transcription factor.
    
 
 0.598
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.