node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APRT | GMPS | ENSCAFP00000029425 | ENSCAFP00000036506 | Adenine phosphoribosyltransferase. | Uncharacterized protein. | 0.986 |
APRT | HPRT1 | ENSCAFP00000029425 | ENSCAFP00000037274 | Adenine phosphoribosyltransferase. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.969 |
APRT | PDE6D | ENSCAFP00000029425 | ENSCAFP00000016354 | Adenine phosphoribosyltransferase. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.900 |
ARL13B | ARL3 | ENSCAFP00000013262 | ENSCAFP00000047245 | ADP ribosylation factor like GTPase 13B. | ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. | 0.684 |
ARL13B | INPP5E | ENSCAFP00000013262 | ENSCAFP00000029099 | ADP ribosylation factor like GTPase 13B. | Inositol polyphosphate-5-phosphatase E. | 0.949 |
ARL13B | PDE6D | ENSCAFP00000013262 | ENSCAFP00000016354 | ADP ribosylation factor like GTPase 13B. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.894 |
ARL2 | PDE6D | ENSCAFP00000035998 | ENSCAFP00000016354 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.843 |
ARL2 | RPGR | ENSCAFP00000035998 | ENSCAFP00000037530 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. | X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. | 0.525 |
ARL3 | ARL13B | ENSCAFP00000047245 | ENSCAFP00000013262 | ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. | ADP ribosylation factor like GTPase 13B. | 0.684 |
ARL3 | PDE6D | ENSCAFP00000047245 | ENSCAFP00000016354 | ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.937 |
ARL3 | RPGR | ENSCAFP00000047245 | ENSCAFP00000037530 | ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. | X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. | 0.606 |
ENSCAFP00000055826 | PDE6D | ENSCAFP00000055826 | ENSCAFP00000016354 | Uncharacterized protein. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.855 |
ENSCAFP00000055826 | RPGR | ENSCAFP00000055826 | ENSCAFP00000037530 | Uncharacterized protein. | X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. | 0.524 |
GMPS | APRT | ENSCAFP00000036506 | ENSCAFP00000029425 | Uncharacterized protein. | Adenine phosphoribosyltransferase. | 0.986 |
GMPS | HPRT1 | ENSCAFP00000036506 | ENSCAFP00000037274 | Uncharacterized protein. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.950 |
GMPS | PDE6D | ENSCAFP00000036506 | ENSCAFP00000016354 | Uncharacterized protein. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.900 |
GUCY1B1 | PDE6D | ENSCAFP00000059398 | ENSCAFP00000016354 | Guanylate cyclase soluble subunit beta-1; Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.827 |
HPRT1 | APRT | ENSCAFP00000037274 | ENSCAFP00000029425 | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | Adenine phosphoribosyltransferase. | 0.969 |
HPRT1 | GMPS | ENSCAFP00000037274 | ENSCAFP00000036506 | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | Uncharacterized protein. | 0.950 |
HPRT1 | PDE6D | ENSCAFP00000037274 | ENSCAFP00000016354 | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes (By similarity). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several order [...] | 0.901 |