STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CALN1Calneuron 1. (261 aa)    
Predicted Functional Partners:
NEURL1B
Neuralized E3 ubiquitin protein ligase 1B.
      
 0.755
TBC1D22A
TBC1 domain family member 22A.
    
 
 0.729
FBXO25
F-box protein 25.
    
 
 0.715
IQSEC3
IQ motif and Sec7 domain 3.
    
 
 0.664
NCDN
Neurochondrin.
   
  
 0.635
PTH2R
Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.633
NCS1
Neuronal calcium sensor 1.
    
 
 0.569
SCAI
Protein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.
      
 0.560
IQSEC1
IQ motif and Sec7 domain 1.
    
 
 0.552
RHOT2
WD repeat domain 90.
   
 
 0.551
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.