STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CALN1Calneuron 1. (261 aa)    
Predicted Functional Partners:
TBC1D22A
TBC1 domain family member 22A.
    
 
 0.722
NCS1
Neuronal calcium sensor 1.
    
 0.712
AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1.
      
 0.692
NEURL1B
Neuralized E3 ubiquitin protein ligase 1B.
      
 0.671
FBXO25
F-box protein 25.
    
 
 0.611
APEH
Acylaminoacyl-peptide hydrolase.
    
 
 0.607
RAB22A
Ras-related protein Rab-22A; Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (By similarity). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
      
 0.591
IQSEC3
IQ motif and Sec7 domain 3.
    
 
 0.590
TMEM236
Transmembrane protein 236.
      
 0.566
PCP4L1
Purkinje cell protein 4 like 1.
    
 
 0.554
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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