STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALKBH2AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (529 aa)    
Predicted Functional Partners:
PARS2
Prolyl-tRNA synthetase 2, mitochondrial.
      
 0.846
ALKBH1
AlkB homolog 1, histone H2A dioxygenase.
   
  
 0.814
IARS2
Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.788
METTL4
Methyltransferase like 4; Belongs to the MT-A70-like family.
   
  
 0.725
YARS1
Tyrosine--tRNA ligase.
  
  
 0.714
AARS2
Alanyl-tRNA synthetase 2, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.710
RPL8
Ribosomal protein L8.
   
 
 0.702
GBE1
1,4-alpha-glucan branching enzyme 1.
  
 
 0.688
EPRS1
Glutamyl-prolyl-tRNA synthetase.
     
 0.681
CSNK2A1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
      
 0.679
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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