STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OXA1LOXA1L mitochondrial inner membrane protein. (414 aa)    
Predicted Functional Partners:
CHCHD1
Coiled-coil-helix-coiled-coil-helix domain containing 1.
    
 
 0.875
MALSU1
Mitochondrial assembly of ribosomal large subunit 1.
  
 0.834
COX2
Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
   
 
 0.834
COQ8A
Coenzyme Q8A.
      
 0.828
DMAC2L
Distal membrane arm assembly complex 2 like.
   
  
 0.816
MRPL47
Mitochondrial ribosomal protein L47.
   
 
 0.811
COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.
      
 0.800
MRPL4
Mitochondrial ribosomal protein L4.
   
 
 0.796
MRPL17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
   
 
 0.772
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.768
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.